The influence of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography on the N- and M-staging and subsequent clinical management of intrahepatic cholangiocarcinoma

PET/CT is superior to conventional imaging in diagnosing lymph node metastasis and distant metastasis, which improves the accuracy of tumor staging from 60.1% to 71.8%, and refines clinical management in 5.8% of ICC patients. PET/CT may bring survival benefits for ICC patients.

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Hepatobiliary Surgery and Nutrition (HBSN) is now a member of the Surgery Journal Editors Group (SJEG)

Beginning in September 2022, the Hepatobiliary Surgery and Nutrition (HBSN) adopted the Surgery Journal Editors Group (SJEG) joint statement and pledges to "strive for diversity in the peer review process and among the editorial boards and editorial leaders."

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Transcatheter arterial embolization-salvaged ALPPS, a novel ALPPS procedure especially for patients with hepatocellular carcinoma and severe fibrosis/cirrhosis

The ALPPS for HCC with fibrosis/cirrhosis is often associated with limited growth of future liver remnant (FLR). The new TAE-Salvaged ALPPS can induce significant FLR increase in patients with HCC and fibrosis/cirrhosis who fail to achieve sufficient FLR hypertrophy after conventional ALPPS stage-1.

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Prospective evaluation of 18F-FDG positron emission tomography in the preoperative staging of patients with hepatic colorectal metastases

A prospective, blinded study comparing utility of 18F-FDG-PET to CT and CT portography as was conducted as staging prior to resection of hepatic colorectal metastases. FDG-PET was found to be an important test, affecting treatment decisions in nearly one-third of patients.

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Peripancreatic vascular involvement in patients with type 1 autoimmune pancreatitis

This study revealed the real-world condition of peripancreatic vascular involvement (PVI) in patients with type 1 autoimmune pancreatitis (AIP) and described independent predictors of PVI development in AIP patients. The follow-up showed majority of PVI lesions achieved an improvement after corticosteroid treatment.

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Validation study of postoperative liver failure and mortality risk scores after liver resection for perihilar cholangiocarcinoma

We validate postoperative liver failure (PHLFS) and mortality risk scores (POMRS) after liver resection for perihilar cholangiocarcinoma, which was established by Western cohort, by Eastern cohort. This external validation study showed that for PHLFS the threshold for discrimination, but the POMRS were not applicable.

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CONGRATULATIONS to Yuman Fong, our senior editorial board member, also a friend of us, elected to National Academy of Medicine

Yuman Fong, M.D., the Sangiacomo Family Chair in Surgical Oncology at City of Hope, a world-renowned cancer research and treatment organization, was presented with one of the highest honors in health and medicine today.

The National Academy of Medicine (NAM) honored Fong “for transforming the fields of liver surgery, robotics in surgery, imaging and display in medicine, and gene therapy.” His contributions as a surgeon, engineer, innovator and mentor have yielded patents and first-in-human trials that translated scientific discoveries to medicines and medical devices.

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Comparison of alternative arterial anastomosis site during liver transplantation when the recipient’s hepatic artery is unusable

During liver transplantation, when the recipient’s hepatic artery is unusable, an arterial anastomosis performed on the recipient’s splenic or coeliac trunk is associated with better intraoperative and postoperative outcomes.

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Gd-EOB-DTPA-enhanced MRI radiomic features for predicting histological grade of hepatocellular carcinoma

Radiomic features based on Gd-EOB-DTPA-enhanced MRI performed well in predicting histological grade of hepatocellular carcinoma, with AUCs of 0.777 to 0.944. Compared with traditional logistic regression model, Artificial neural network showed potential advantages in distinguishing between high-grade and low-grade HCCs.

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Chinese expert consensus on conversion therapy for hepatocellular carcinoma (2021 edition)

Therapeutic advances in advanced hepatocellular carcinoma have increased the opportunity for patients with initially unresectable disease to achieve tumor downstaging and undergo surgical resection, a ‘conversion therapy’. We reviewed current evidence for conversion therapy in HCC and developed expert consensus statements to guide clinical practice.

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A novel radiomics signature based on T2-weighted imaging accurately predicts hepatic inflammation in individuals with biopsy-proven nonalcoholic fatty liver disease: a derivation and independent validation study

This is the largest single study to assess the prediction of histologic hepatic inflammation by radiomics in NAFLD to date. A radiomics signature based on T2 weighted magnetic resonance imaging non-invasively and accurately identifies severe hepatic inflammation in patients with biopsy-proven NAFLD.

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Hepatobiliary Surgery and Nutrition (HBSN) is now a member of Committee on Publication Ethics (COPE)

Starting from July 2021, AME Publishing Company is formally recognized a publisher member of Committee on Publication Ethics (COPE) and over 60 AME-published journals become a member of Committee on Publication Ethics (COPE), as part of AME’s commitment to best practice in scholarly publishing. Hepatobiliary Surgery and Nutrition (HBSN) is among the list of COPE membership.

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Liver resection versus liver transplantation for hepatocellular carcinoma within Milan criteria: a meta-analysis of 18,421 patients

LR was associated with poorer OS (HR 1.44, CI: 1.14-1.81, p<0.01) and DFS (HR 2.71, CI: 2.23-3.28, p<0.01) compared to LT. In uninodular HCC, OS was comparable between LR and LT (p=0.13), but DFS remained poorer (p<0.01). Cohorts that underwent enhanced surveillance had comparable OS between LR and LT (p=0.33).

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Associating liver partition and portal vein ligation for staged hepatectomy versus sequential transarterial chemoembolization and portal vein embolization in staged hepatectomy for HBV-related hepatocellular carcinoma: a randomized comparative study

This article provides relatively high-level evidence about the merits and demerits of ALPPS compared with PVE, especially in patients with HBV related HCC, pointing out the higher resection rates and longer OS of ALPPS at the cost of a higher postoperative morbidity rate.

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Development and internal validation of the Comprehensive ALPPS Preoperative Risk Assessment (CAPRA) score: is the patient suitable for Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS)?

The CAPRA Score, based on patient condition and type of procedure, has excellent preoperative prediction of 90-day mortality risk in ALPPS. It therefore provides additional support in patient selection and procedure planning, in combination with already validated scores, volumetry and liver function assessments.

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Intraoperative reperfusion assessment of human pancreas allografts using hyperspectral imaging (HSI)

This article describes the first application of hyperspectral imaging in human pancreas allografts. Our novel non-invasive technique is capable to deliver real time visual and quantitative information about the tissue oxygenation, perfusion as well as hemoglobin and water concentration of the organ, subject to investigation.

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Preservation of aberrant right hepatic arteries does not affect safety and oncological radicality of pancreaticoduodenectomy—own results and a systematic review of the literature

The aim of the present study was to investigate the incidence and management of aRHA in a large cohort of consecutive PD and to assess its effect on the surgical and oncological outcomes, and to compare the results to those already available in the literature.

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