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Original Article

Liver venous deprivation versus portal vein embolization before major hepatectomy: future liver remnant volumetric and functional changes
Boris Guiu, François Quenet, Fabrizio Panaro, Lauranne Piron, Christophe Cassinotto, Astrid Herrerro, François-Régis Souche, Margaux Hermida, Marie-Ange Pierredon-Foulongne, Ali Belgour, Serge Aho-Glele, Emmanuel Deshayes
Based on serial measurements, liver venous deprivation (embolization of both portal and hepatic vein(s)) gives greater volume and functional gain of the future liver remnant, as compared to portal vein embolization.
Adjuvant chemotherapy for intrahepatic cholangiocarcinoma: approaching clinical practice consensus?
Ariella M. Altman, Scott Kizy, Schelomo Marmor, Jane Y. C. Hui, Todd M. Tuttle, Eric H. Jensen, Jason W. Denbo
Limited potential of resolvin D1 in treatment of cholestatic liver fibrosis
Kerstin Abshagen, Alexander Hartmann, Laura Grüner, Marie Liebig, Brigitte Vollmar
Dietary supplementation of health-promoting n-3 PUFAs and their mediators may be promising therapeutic agents for chronic liver disease. However, the anti-inflammatory and ant-fibrotic potential of the DHA mediator resolvin D1 is limited in mice with cholestatic liver disease, as disease progression could not be prevented.

Review Article

The beneficial effects of intermittent fasting: an update on mechanism, and the role of circadian rhythm and gut microbiota
Dandan Hu, Zhibo Xie, Yuqian Ye, Suhad Bahijri, Minshan Chen
The current situation of food surplus has made us aware of the dangers of metabolic syndrome, and of the health benefits of fasting. In particular, the intermittent fasting regimen values more via remodeling the circadian clock and gut microbiota.

Review Article on Imaging and HPB Surgery1

Use of imaging as staging and surgical planning for pancreatic surgery
Andrew Hieu Nguyen, Laleh G. Melstrom
Modern imaging modalities are indispensable in the pre-operative staging and surgical planning in pancreatic surgery. This review discusses staging and resectability, as well as the imaging modalities used in the pre-operative assessment of patients with pancreatic tumors.
Fluorescence-guided hepatobiliary surgery with long and short wavelength fluorophores
Thinzar M. Lwin, Robert M. Hoffman, Michael Bouvet
Fluorescence-guided surgery for hepatobiliary procedures is a relatively new and developing field. The approaches to use of fluorophores for clinical intra-operative image-guidance during HPB surgery is reviewed.


Clinical implications of the dual blockade of the PD-1/PD-L1 and vascular endothelial growth factor axes in the treatment of hepatocellular carcinoma
Naoshi Nishida
Is there a safe threshold for alcohol consumption in nonalcoholic fatty liver disease?
Mimi Kim, Dae Won Jun
Ampullary adenocarcinoma: the current state of adjuvant therapies
Charles C. Vining, Darryl Schuitevoerder, Kiran K. Turaga
Is robotic pancreatic surgery finally ready for prime-time?
Andrew A. Gumbs, Roland Croner, Elie Chouillard
The Mediterranean diet and nonalcoholic fatty liver disease in individuals at high cardiovascular risk
Seyedeh Tayebeh Rahideh, Farzad Shidfar
Does laparoscopic liver resection for colorectal liver metastases provide a true survival benefit compared with open liver resection?
Shinichi Akahoshi, Toru Beppu, Yasuhisa Mori, Koichi Kinoshita, Nobutaka Sato, Ken Kikuchi
FIB-4 score and hepatocellular carcinoma risk after hepatitis C virus cure: time to revise surveillance?
Antonio Saviano, Simona Tripon, Thomas F. Baumert
Liver transplantation for unresectable colorectal metastasis: a new hope
Andre Gorgen, Tommy Ivanics, Gonzalo Sapisochin
Impact of nutritional status on outcome of pancreatic resections for pancreatic cancer and periampullary tumors
Vittorio Grazio Perrone, Sara Iacopi, Gabriella Amorese, Ugo Boggi
Robotic pancreatic surgery: a slowly developing field
Patrick N. Salibi, John B. Martinie
Hepatocellular carcinoma chemoprevention in chronic hepatitis B patients: all-in on statins?
José Ursic-Bedoya, Boris Guiu


1. The series “Imaging and HPB Surgery”was commissioned by the editorial office, Hepatobiliary Surgery and Nutrition without any sponsorship or funding. Yuman Fong, Dana Haddad and Warner Susanne are serving as the unpaid Guest Editors for the series.

Review Article

Histamine regulation of pancreatitis and pancreatic cancer: a review of recent findings
Taylor Francis, Allyson Graf, Kyle Hodges, Lindsey Kennedy, Laura Hargrove, Mattie Price, Kate Kearney, Heather Francis
Liver transplantation for hepatocellular carcinoma
Jerome Byam, John Renz, J. Michael Millis
Hilar cholangiocarcinoma: diagnosis, treatment options, and management
Kevin C. Soares, Ihab Kamel, David P. Cosgrove, Joseph M. Herman, Timothy M. Pawlik

Original Articles

Correlation between 3D-MRCP and intra-operative findings in right liver donors
Aly Ragab, Reyold I. Lopez-Soler, Aytekin Oto, Giuliano Testa
Diagnosis and treatment of hepatic angiomyolipoma
Shunda Du, Ying Li, Yilei Mao, Xinting Sang, Xin Lu, Wenze Wang, Qing Zhang, Huadan Xue, Xiaobo Yang, Shaohua Li, Tianyi Chi, Shouxian Zhong, Jiefu Huang
Liver transplantation in mainland China: the overview of CLTR 2011 annual scientific report
Haibo Wang, Wenshi Jiang, Zhiye Zhou, Jianyan Long, Wen Li, Sheung Tat Fan
Cytochrome P450 2E1 inhibition prevents hepatic carcinogenesis induced by diethylnitrosamine in alcohol-fed rats
Qinyuan Ye, Fuzhi Lian, Pollyanna R.G. Chavez, Jayong Chung, Wenhua Ling, Hua Qin, Helmut K. Seitz, Xiang-Dong Wang

Original Article

Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes
Anastasia Renzi, Romina Mancinelli, Paolo Onori, Antonio Franchitto, Gianfranco Alpini, Shannon Glaser, Eugenio Gaudio

Review Article

Melatonin regulation of biliary functions
Shannon Glaser, Yuyan Han, Heather Francis, Gianfranco Alpini


Risk stratification for Hepatitis B treatment in the molecular age
Sanjay R. Mehta, Alexander Kuo

Original Articles

Cytochrome P450 2E1 inhibition prevents hepatic carcinogenesis induced by diethylnitrosamine in alcohol-fed rats
Qinyuan Ye, Fuzhi Lian, Pollyanna R.G. Chavez, Jayong Chung, Wenhua Ling, Hua Qin, Helmut K. Seitz, Xiang-Dong Wang
Effect of tomato extract supplementation against high-fat diet-induced hepatic lesions
Antonio J. Melendez-Martinez, Andre F. Nascimento, Yan Wang, Chun Liu, Yilei Mao, Xiang-Dong Wang

Review Articles on Liver Immunology: Part 2

Contribution of bone marrow-derived fibrocytes to liver fibrosis
Jun Xu, Min Cong, Tae Jun Park, David Scholten, David A. Brenner, Tatiana Kisseleva

Original Article on Fatty Liver Disease and Nutrient Intervention: Part 1

Inhibition of diethylnitrosamine-initiated alcohol-promoted hepatic inflammation and precancerous lesions by flavonoid luteolin is associated with increased sirtuin 1 activity in mice
Bruna Paola Murino Rafacho, Camilla Peach Stice, Chun Liu, Andrew S. Greenberg, Lynne M. Ausman, Xiang-Dong Wang

Original Article on Fatty Liver Disease and Nutrient Intervention: Part 2

DGAT1-deficiency affects the cellular distribution of hepatic retinoid and attenuates the progression of CCl4-induced liver fibrosis
Jason J. Yuen, Seung-Ah Lee, Hongfeng Jiang, Pierre-Jacques Brun, William S. Blaner

Review Article on Retinoid Biology: Part I

STRA6: role in cellular retinol uptake and efflux
Mary Kelly, Johannes von Lintig

Original Article on Retinoid Biology: Part I

Alcohol exposure in utero perturbs retinoid homeostasis in adult rats
Youn-Kyung Kim, Michael V. Zuccaro, Changqing Zhang, Dipak Sarkar, Loredana Quadro

Below are the latest Hepatobiliary Surgery and Nutrition articles published online ahead of print publication.



Original Article

Review Article

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