Publish Ahead of Print


Refining selection criteria to further increase survival benefit in liver transplantation for unresectable colorectal liver metastases
Matteo Serenari, Matteo Ravaioli
Clinical implications of the dual blockade of the PD-1/PD-L1 and vascular endothelial growth factor axes in the treatment of hepatocellular carcinoma
Naoshi Nishida
Vessels encapsulating tumor clusters in hepatocellular carcinoma: a unique and valuable pathological imaging
Yo-ichi Yamashita, Hideo Baba
Faecal microbiota transplantation as an elixir of youth
Craig Haifer, Sudarshan Paramsothy, Rupert W. Leong
Risk stratification of HCC occurrence after HCV eradication: a complicate plot of risk factors related and unrelated to the previous viral disease
Valentina Cossiga, Maria Guarino, Filomena Morisco, Nicola Caporaso
Nonalcoholic fatty liver disease in type 2 diabetes: awareness is the first step toward change
Fernando Bril
Probiotics and synbiotics targeting the intestinal microbiome attenuate non-alcoholic fatty liver disease
Luis Vitetta, Jeremy D. Henson
Evaluating the application of next generation sequencing techniques in endoscopic retrograde cholangiopancreatography (ERCP) to improve diagnostic accuracy in patients with malignant biliary strictures
Tan To Cheung
Locally advanced pancreatic cancer: staging, operability, and the importance of multimodality therapy
Rebecca Y. Kim, Douglas B. Evans, Kathleen K. Christians
The rapidly expanding role of thermal ablation in the treatment of colorectal liver metastases
Martijn R. Meijerink, M. Petrousjka van den Tol, Robbert S. Puijk
Ampullary adenocarcinoma: the current state of adjuvant therapies
Charles C. Vining, Darryl Schuitevoerder, Kiran K. Turaga
Hepatocellular carcinoma and liver transplant: beyond the Milan criteria and the risk of “short-blanket” syndrome
Stefano Gitto, Stefano Di Sandro, Paolo Magistri, Pietro Andreone, Fabrizio Di Benedetto
Nonalcoholic fatty liver disease and type 2 diabetes: a burgeoning problem with unclear solutions
Mariana Lazo, Jeanne M. Clark
Clinical outcomes after treatment with direct-acting antivirals: not all concern hepatocellular carcinoma risk
Elton Dajti, Federico Ravaioli, Davide Festi, Antonio Colecchia
Perspectives on immunotherapy utilization for hepatobiliary cancers in the United States
Pedro Luiz Serrano Usón Junior, Daniel Ahn, Mohamad Bassam Sonbol, Tanios Bekaii-Saab, Mitesh J. Borad
Is there a safe threshold for alcohol consumption in nonalcoholic fatty liver disease?
Mimi Kim, Dae Won Jun
The Mediterranean diet and nonalcoholic fatty liver disease in individuals at high cardiovascular risk
Seyedeh Tayebeh Rahideh, Farzad Shidfar
Does laparoscopic liver resection for colorectal liver metastases provide a true survival benefit compared with open liver resection?
Shinichi Akahoshi, Toru Beppu, Yasuhisa Mori, Koichi Kinoshita, Nobutaka Sato, Ken Kikuchi
Pediatric NAFLD: lessons from the gut
Laura Iogna Prat, Emmanuel A. Tsochatzis
Liver transplantation for unresectable colorectal metastasis: a new hope
Andre Gorgen, Tommy Ivanics, Gonzalo Sapisochin
Is robotic pancreatic surgery finally ready for prime-time?
Andrew A. Gumbs, Roland Croner, Elie Chouillard
FIB-4 score and hepatocellular carcinoma risk after hepatitis C virus cure: time to revise surveillance?
Antonio Saviano, Simona Tripon, Thomas F. Baumert
Hepatocellular carcinoma chemoprevention in chronic hepatitis B patients: all-in on statins?
José Ursic-Bedoya, Boris Guiu
Management of recurrent hepatocellular carcinoma after resection
Hwee Leong Tan, Brian K. P. Goh
Clinical impact of omega-3 fatty acids (Ω3 FA) supplementation on liver surgery
Jean Gugenheim, Niccolo Petrucciani
A new tool for estimating liver cancer risk after a hepatitis C virus cure
Hamish Innes, William L. Irving
Promising anticancer therapy: combination of immune checkpoint inhibitors and molecular-targeted agents
Toshiharu Sakurai, Naoshi Nishida, Masatoshi Kudo
Targeting tumor microenvironment as a treatment strategy for hepatocellular carcinoma
Zuyuan Lin, Xiaonan Xiang, Di Lu, Xiao Xu
Assessing resectability for colorectal liver metastases: agreeing that we disagree
Luis I. Ruffolo, Koji Tomiyama, Roberto Hernandez-Alejandro
Robotic pancreatic surgery: a slowly developing field
Patrick N. Salibi, John B. Martinie
Laparoscopic surgery for colorectal liver metastases: moving forward while keeping feet on the ground
Mariano Cesare Giglio, Roberto Ivan Troisi
Hepatitis C—committing the world to an eradication of the infection
Johannes Wiegand, Thomas Berg
The gut-liver axis as a target of liver disease management
Claudia Mandato, Anna Pia Delli Bovi, Pietro Vajro
Current status of treatment for colorectal liver metastases in the United Kingdom
Kentaro Okamoto, Hiroyuki Uetake
Addressing the variation in hepatic surgery for colorectal liver metastasis
Rachel V. Guest, Kjetil Søreide
A new era of systemic therapy for intermediate and advanced stage hepatocellular carcinoma
Masatoshi Kudo


Challenges in elucidating cholangiocarcinoma etiology
Sarah S. Jackson, Andrea A. Florio, Katherine A. McGlynn, Jessica L. Petrick

Original Article

Prospective study to evaluate the prognostic value of different nutritional assessment scores in liver surgery: NURIMAS Liver (DRKS00006340)
Pascal Probst, Juri Fuchs, Michael R. Schön, Georgios Polychronidis, Christos Stravodimos, Arianeb Mehrabi, Markus K. Diener, Philipp Knebel, Markus W. Büchler, Katrin Hoffmann
Adjuvant chemotherapy for intrahepatic cholangiocarcinoma: approaching clinical practice consensus?
Ariella M. Altman, Scott Kizy, Schelomo Marmor, Jane Y. C. Hui, Todd M. Tuttle, Eric H. Jensen, Jason W. Denbo
Limited potential of resolvin D1 in treatment of cholestatic liver fibrosis
Kerstin Abshagen, Alexander Hartmann, Laura Grüner, Marie Liebig, Brigitte Vollmar
Severity of early allograft dysfunction following donation after circulatory death liver transplantation: a multicentre study
Kun Wang, Di Lu, Yuhui Liu, Wangyao Li, Li Zhuang, Zhenyu Ma, Qinfen Xie, Binhua Pan, Yichao Wu, Junli Chen, Lidan Lin, Xiaowen Feng, Qiang Wei, Xuyong Wei, Haiyang Xie, Zhengxin Wang, Shusen Zheng, Xiao Xu
Mutation profile and its correlation with clinicopathology in Chinese hepatocellular carcinoma patients
Shuo Wang, Huasheng Shi, Tao Liu, Manjiang Li, Sanshun Zhou, Xuan Qiu, Zusen Wang, Weiyu Hu, Weidong Guo, Xiaoqian Chen, Honglin Guo, Xiaoliang Shi, Junping Shi, Yunjin Zang, Jingyu Cao, Liqun Wu
A new classification for hepatocellular carcinoma with hepatic vein tumor thrombus
Zhen-Hua Chen, Kang Wang, Xiu-Ping Zhang, Jing-Kai Feng, Zong-Tao Chai, Wei-Xing Guo, Jie Shi, Meng-Chao Wu, Wan Yee Lau, Shu-Qun Cheng
Role of C11-FDG dual-tracer PET-CT scan in metastatic screening of hepatocellular carcinoma—a cost-effectiveness analysis
Kevin K. W. Chu, Albert C. Y. Chan, Ka Wing Ma, Wong Hoi She, Wing Chiu Dai, Kenneth S. H. Chok, Tan To Cheung, Chung Mau Lo
How should liver hypertrophy be stimulated? A comparison of upfront associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and portal vein embolization (PVE) with rescue possibility
Ernesto Sparrelid, Kristina Hasselgren, Bård Ingvar Røsok, Peter Nørgaard Larsen, Nicolai Aagaard Schultz, Ulrik Carling, Eva Fallentin, Stefan Gilg, Per Sandström, Gert Lindell, Bergthor Björnsson
The impact of standardized methods of hepatic vein reconstruction with an external iliac vein graft
Fumihiro Terasaki, Yuji Kaneoka, Atsuyuki Maeda, Yuichi Takayama, Yasuyuki Fukami, Takamasa Takahashi, Masahito Uji
New-onset diabetes after adult liver transplantation in the Korean Organ Transplantation Registry (KOTRY) study
Jong Man Kim, Shin Hwang, Kwang-Woong Lee, Jae-Geun Lee, Je Ho Ryu, Bong-Wan Kim, Dong Lak Choi, Young Kyoung You, Dong-Sik Kim, Yang Won Nah, Koo Jeong Kang, Jai Young Cho, Geun Hong, In Seok Choi, Hee Chul Yu, Dongho Choi, Myoung Soo Kim, The Korean Organ Transplantation Registry Study Group
The benefit of curative liver resection with a selective bile duct preserving approach for hepatocellular carcinoma with macroscopic bile duct tumor thrombus
Anon Chotirosniramit, Akkaphod Liwattanakun, Sunhawit Junrungsee, Wasana Ko-iam, Trichak Sandhu, Worakitti Lapisatepun
Machine learning predicts unpredicted deaths with high accuracy following hepatopancreatic surgery
Kota Sahara, Anghela Z. Paredes, Diamantis I. Tsilimigras, Kazunari Sasaki, Amika Moro, J. Madison Hyer, Rittal Mehta, Syeda A. Farooq, Lu Wu, Itaru Endo, Timothy M. Pawlik
The beneficial impacts of splanchnic vasoactive agents on hepatic functional recovery in massive hepatectomy porcine model
Hye-Sung Jo, Jae Hyun Han, Yoon Young Choi, Jin-I Seok, Young-In Yoon, Dong-Sik Kim
Clear mortality gap caused by graft macrosteatosis in Chinese patients after cadaveric liver transplantation
Zhengtao Liu, Wenchao Wang, Li Zhuang, Jingfeng Liu, Shuping Que, Dan Zhu, Linfang Dong, Jian Yu, Lin Zhou, Shusen Zheng
High HbA1c is a risk factor for complications after hepatectomy and influences for hepatocellular carcinoma without HBV and HCV infection
Shingo Shimada, Toshiya Kamiyama, Tatsuya Orimo, Akihisa Nagatsu, Hirofumi Kamachi, Akinobu Taketomi
A combined Cox and logistic model provides accurate predictive performance in estimation of time-dependent probabilities for recurrence of intrahepatic cholangiocarcinoma after resection
Seogsong Jeong, Guijuan Luo, Qiang Gao, Jing Chen, Xiaolong Liu, Liangqing Dong, Yongjie Zhang, Feng Shen, Qingbao Cheng, Chengjun Sui, Jingfeng Liu, Hongyang Wang, Qiang Xia, Lei Chen
Liver venous deprivation versus portal vein embolization before major hepatectomy: future liver remnant volumetric and functional changes
Boris Guiu, François Quenet, Fabrizio Panaro, Lauranne Piron, Christophe Cassinotto, Astrid Herrerro, François-Régis Souche, Margaux Hermida, Marie-Ange Pierredon-Foulongne, Ali Belgour, Serge Aho-Glele, Emmanuel Deshayes
A simple scoring system to estimate perioperative mortality following liver resection for primary liver malignancy—the Hepatectomy Risk Score (HeRS)
Dimitrios Moris, Brian I. Shaw, Cecilia Ong, Ashton Connor, Mariya L. Samoylova, Samuel J. Kesseli, Nader Abraham, Jared Gloria, Robin Schmitz, Zachary W. Fitch, Bryan M. Clary, Andrew S. Barbas
The potential use of extended criteria donors and eligible recipients in liver transplantation for unresectable colorectal liver metastases in Central Sweden
Christina Villard, Joakim Westman, Jonas Frank, Oystein Jynge, Ernesto Sparrelid, Carl Jorns
Liver transplantation: would it be the best and last chance of cure for hepatocellular carcinoma with major venous invasion?
Ka Wing Ma, Albert Chi Yan Chan, Kenneth Siu Ho Chok, Wong Hoi She, Tan To Cheung, Wing Chiu Dai, James Yan Yue Fung, Chung Mau Lo
Robotic-assisted versus open total pancreatectomy: a propensity score-matched study
Yuanchi Weng, Mengmin Chen, Georgios Gemenetzis, Yusheng Shi, Xiayang Ying, Xiaxing Deng, Chenghong Peng, Jiabin Jin, Baiyong Shen
Liver resection versus intensity-modulated radiation therapy for treatment of hepatocellular carcinoma with hepatic vein tumor thrombus: a propensity score matching analysis
Zhen-Hua Chen, Xiu-Ping Zhang, Shuang Feng, Jing-Kai Feng, Zong-Tao Chai, Wei-Xing Guo, Jie Shi, Wan Yee Lau, Yan Meng, Shu-Qun Cheng
Stereotactic body radiation therapy versus radiofrequency ablation in patients with small hepatocellular carcinoma: a systematic review and meta-analysis
Jiawei Hong, Linping Cao, Haiyang Xie, Yuanxing Liu, Jun Yu, Shusen Zheng
Impact of body mass index on hepatocellular carcinoma recurrence after liver transplantation through long-term follow-up
Nada El-domiaty, Faouzi Saliba, Vincent Karam, Rodolphe Sobesky, Wafaa Ibrahim, Eric Vibert, Gabriella Pittau, Khaled Amer, Maysaa A. Saeed, Jihan A. Shawky, Daniel Cherqui, René Adam, Didier Samuel
Transarterial infusion chemotherapy with FOLFOX for advanced hepatocellular carcinoma: a multi-center propensity score matched analysis of real-world practice
Shaohua Li, Jie Mei, Qiaoxuan Wang, Feng Shi, Hongyan Liu, Ming Zhao, Lianghe Lu, Yihong Ling, Zhixing Guo, Yabing Guo, Xiaoming Chen, Ming Shi, Wan Yee Lau, Wei Wei, Rongping Guo
Pembrolizumab combined with lenvatinib as non-first-line therapy in patients with refractory biliary tract carcinoma
Jianzhen Lin, Xu Yang, Junyu Long, Songhui Zhao, Jinzhu Mao, Dongxu Wang, Yi Bai, Jin Bian, Lei Zhang, Xiaobo Yang, Anqiang Wang, Fucun Xie, Weiwei Shi, Huayu Yang, Jie Pan, Ke Hu, Mei Guan, Lin Zhao, Li Huo, Yilei Mao, Xinting Sang, Kai Wang, Haitao Zhao
Development and validation of a machine learning-based nomogram for prediction of intrahepatic cholangiocarcinoma in patients with intrahepatic lithiasis
Xian Shen, Huanhu Zhao, Xing Jin, Junyu Chen, Zhengping Yu, Kuvaneshan Ramen, Xiangwu Zheng, Xiuling Wu, Yunfeng Shan, Jianling Bai, Qiyu Zhang, Qiqiang Zeng
The presence of NAFLD in nonobese subjects increased the risk of metabolic abnormalities than obese subjects without NAFLD: a population-based cross-sectional study
Ping-Fang Hu, Xin Zeng, Zi-Yuan Zou, Wei Tang, Yi-Bin Guo, Zong-Li Yuan, Pei-Mei Shi, Yu Tan, Yan Song, Yong-Quan Shi, Wei-Fen Xie

Review Article

Use of imaging as staging and surgical planning for pancreatic surgery
Andrew Hieu Nguyen, Laleh G. Melstrom
Renewed considerations on the utility (or the futility) of hepatic resections for breast cancer liver metastases
Gian Luca Grazi
The role of associating liver partition and portal vein ligation for staged hepatectomy in the management of patients with colorectal liver metastasis
Juan Glinka, Victoria Ardiles, Juan Pekolj, Eduardo de Santibañes, Martin de Santibañes
Biliary complications after liver transplantation: current perspectives and future strategies
Bianca Magro, Matteo Tacelli, Alessandra Mazzola, Filomena Conti, Ciro Celsa
Hepatocellular carcinoma in non-alcoholic fatty liver disease—a review of an emerging challenge facing clinicians
Daniel Geh, Derek M. Manas, Helen L. Reeves
Fluorescence-guided hepatobiliary surgery with long and short wavelength fluorophores
Thinzar M. Lwin, Robert M. Hoffman, Michael Bouvet
Impact and clinical usefulness of genetic data in the surgical management of colorectal cancer liver metastasis
Georgios Antonios Margonis, Martin E. Kreis, Jaeyun Jane Wang, Carsten Kamphues, Christopher L. Wolfgang, Matthew J. Weiss
Neuroendocrine liver metastases: a contemporary review of treatment strategies
Jordan M. Cloyd, Aslam Ejaz, Bhavana Konda, Mina S. Makary, Timothy M. Pawlik
A review on radiofrequency, microwave and high-intensity focused ultrasound ablations for hepatocellular carcinoma with cirrhosis
Tan To Cheung, Ka Wing Ma, Wong Hoi She

Letter to the Editor

Synchronous occurrence of hepatocellular carcinoma and multiple biliary hamartomas mimicking hepatocellular carcinoma with multiple intra-hepatic metastases
Yu Huang, Zhou Ye, Yang Kong, Dong-Kai Zhou, Li-Xiong Ying, Wei-Lin Wang
The origin of newborn hepatocytes in associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)-derived regeneration
Yifan Tong, Yongfen Zhu, Xiujun Cai
Not yet IDEAL?—evidence and learning curves of minimally invasive pancreaticoduodenectomy
Felix Nickel, Caelán Max Haney, Beat-Peter Müller-Stich, Thilo Hackert
Automated quantification of fibrosis-related parameters using dual-photon microscopy replace diagnosis of pathologists in NAFLD
Yoshio Sumida, Takeshi Okanoue, Atsushi Nakajima, Japan Study Group of NAFLD (JSG-NAFLD)
Poor dietary intake improved by total excision of oral cavity metastases in a patient with hepatocellular carcinoma and elevated myeloid-derived suppressor cells
Ching Chang, Chien-Hao Huang
Prevent bile duct injury by indocyanine green guide fluorescent imaging during laparoscopic cholecystectomy in liver transplantation recipient
Chee-Chien Yong, Shih-Min Yin, Yi-Ping Sng, Chao-Long Chen
Staged ligation of large portosystemic collaterals in living donor liver transplantation using a small-for-size graft
Chao-Long Chen, Chee-Chien Yong, Jeffrey Samuel Co, Chih-Yi Chen, Aldwin Ong, Chih-Che Lin, Yu-Fan Cheng