The Story Behind the Cover Picture
Original Article
Nonalcoholic steatohepatitis critically rewires the ischemia/reperfusion-induced dysregulation of cardiolipins and sphingolipids in mice
Nonalcoholic steatohepatitis critically promotes the I/R-induced decreases of cardiolipins and increase of ceramides, which is linked to the exaggerated I/R injury in the mouse liver of nonalcoholic steatohepatitis.
Nab-paclitaxel plus tegafur gimeracil oteracil potassium capsule (S-1) as first-line treatment for advanced biliary tract adenocarcinoma: a phase 2 clinical trial
The novel combination of nab-paclitaxel plus S-1 as first-line treatment for advanced biliary tract adenocarcinoma yieled comparable efficacy to the standard regimens in terms of ORR, PFS and OS. The favorable tolerability makes it a potential selection of non-platinum and -gemcitabine-based regimen.
Review Article
A narrative review of the current and future role of robotic surgery in liver surgery and transplantation
The article reviewed the role of minimally invasive surgery in the field of liver surgery and transplantation, with a particular focus on the robotic approach. Robotic surgery, especially in living donation, can be performed safely in properly selected patients by teams with high expertise.
Surgery for metastatic pancreatic neuroendocrine tumors: a narrative review
Surgery remains the best treatment for localized PanNETs, but it also has an important role in metastatic disease. Surgical debulking of liver metastasis in selected patients with metastatic PanNETs may confer a survival benefit, improve symptoms, and allow systemic therapies to be more efficacious.
Editorial
Editorial Commentary
Viewpoint
Letter to the Editor
