Vol 11, No 6 (December 01, 2022): Hepatobiliary Surgery and Nutrition

Original Article

Combined non-alcoholic fatty liver disease and type 2 diabetes in severely obese patients—medium term effects of sleeve gastrectomy versus Roux-en-Y-gastric bypass on disease markers
Franck Billmann, Sherehan El Shishtawi, Tom Bruckner, Mostafa ElSheikh, Beat Peter Müller-Stich, Adrian Billeter
Our retrospective pair-matched analysis suggests that bariatric surgery with Sleeve Gastrectomy may be preferable to Roux-Y-Gastric Bypass for obese patients with NAFLD and Type 2 Diabetes Mellitus based on the medium-term rates of remission of markers of these co-morbidities.
Propensity score matching study of 325 patients with spontaneous rupture of hepatocellular carcinoma
Wei Wang, Tao Meng, Ying Chen, Ye-Chuan Xu, Yi-Jun Zhao, Yan Zhang, Ming-Ya Yang, Zhi-Hua Zhang, Fan Huang, Hong-Chuan Zhao, Xiao-Ping Geng, Li-Xin Zhu
Ruptured hepatocellular carcinoma (RHCC) is a serious bleeding complication with a high mortality. Emergency trans-arterial embolization (TAE) plus two-stage hepatectomy might be the optimal treatment for patients with RHCC, which prognosis were no significant difference from that of non-ruptured HCC patients who undergoing hepatectomy.
International assessment and validation of the prognostic role of lymph node ratio in patients with resected pancreatic head ductal adenocarcinoma
Gaëtan-Romain Joliat, Ismail Labgaa, Jesse Sulzer, Dionisios Vrochides, Alessandro Zerbi, Gennaro Nappo, Julie Perinel, Mustapha Adham, Stijn van Roessel, Marc G. Besselink, J. Sven D. Mieog, Jesse V. Groen, Nicolas Demartines, Markus Schäfer
This international multicenter cross-sectional study (n=1327) demonstrated that lymph node ratio (LNR) was a strong overall survival (OS) predictor in the entire cohort of patients with resected pancreatic head ductal adenocarcinoma and in patients with lymph node involvement. Furthermore, patients with LNR<0.225 had better OS than patients with LNR≥0.225.
Serum metabolic effects of corn oligopeptides with 7-day supplementation on early post-surgery primary liver cancer patients: a double-blind randomized controlled trial
Weiqi Rong, Hui Xia, Kai Zhang, Yihan Zhang, Changcheng Tao, Fan Wu, Liming Wang, Hong Zhang, Guiju Sun, Jianxiong Wu
Characteristics and outcomes of hepatocellular carcinoma patients with macrovascular invasion following surgical resection: a meta-analysis of 40 studies and 8,218 patients
Daniel Q. Huang, Andrew Tran, Eunice X. Tan, Sanjna N. Nerurkar, Readon Teh, Margaret L. P. Teng, Ee Jin Yeo, Biyao Zou, Connie Wong, Carlos O. Esquivel, C. Andrew Bonham, Mindie H. Nguyen
In this meta-analysis, we determined that hepatocellular carcinoma patients with macrovascular invasion who underwent resection had a poor overall survival. However, among patients with 2nd order portal vein tumor thrombus, median survival was 20 months, suggesting that surgical resection may be considered in selected patients.


Peri-hospital care: time to have a system for arranging patient care before and after hospitalization
Jirun Peng
Atezolizumab plus bevacizumab for patients with Child-Pugh-B in hepatocellular carcinoma
Shinji Itoh, Masafumi Ikeda
High volume transplant experience is beneficial but not mandatory for the performance of complex liver resections
Reed Ayabe, Jean-Nicolas Vauthey, Hop S. Tran Cao
Precision oncology and molecular therapies for hepatocellular carcinoma
Liming Chen, Youcai Xu, Gu Li
Can metabolomic signature foster precision medicine approaches in nonalcoholic fatty liver disease arena?
Amedeo Lonardo
In search of a roadmap towards improving care of patients with cirrhosis and ascites, could a platform trial design transform clinical research?
Alastair O’Brien
Surgical Infection Society guidelines on antibiotic use in gallstone surgery: high time we crack down on prophylactic antibiotics
Gabriel Sandblom
Highlights of constructing liver-relevant in vitro models with 3D bioprinting
Jiangang Zhang, Huiyu Yang, Huayu Yang
Evolution of systemic therapy for advanced-stage hepatocellular carcinoma
Moon Haeng Hur, Yoon Jun Kim
Management of severe acute pancreatitis: all hands to the pump
Yousuke Nakai
Perioperative management of patients with liver cancer complicated with sarcopenia
Jiali Xing, Xueshuai Wan, Xinting Sang, Huayu Yang, Shunda Du
Cystic liver lesions: from diagnosis to recognition of complications and when to treat
Sarah Lowry, Wikrom Karnsakul
New guidelines for the treatment of severe acute pancreatitis
Gabriel L. Oland, O. Joe Hines
Advances in 3D bioprinting technology for liver regeneration
Changcan Li, Zhuoran Jiang, Huayu Yang