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Liver resection for multifocal hepatocellular carcinoma: is it an option?

   
@article{HBSN26020,
	author = {Luca Viganò and Guido Costa and Luca Di Tommaso},
	title = {Liver resection for multifocal hepatocellular carcinoma: is it an option?},
	journal = {Hepatobiliary Surgery and Nutrition},
	volume = {8},
	number = {5},
	year = {2019},
	keywords = {},
	abstract = {Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. At first diagnosis, HCC is multifocal in about 35–40% of patients (1,2). According to Western guidelines, the treatment of multifocal (non-metastatic) HCC is well codified: transplantation is indicated for HCCs within Milan criteria (2–3 nodules ≤30 mm), ablation for non-transplantable HCCs within Milan criteria, and chemoembolization for the remaining patients (3). Liver resection has no role. Daily practice is much more complex. The term multinodular HCC encompasses a wide range of scenarios, from oligonodular to diffuse disease, from multicentric to metastatic tumors, that require a case-by-case tailored treatment. We are still far from a real solution and several issues deserve further investigations, including the role of surgery, as highlighted by the recently published Japanese series of liver resections for multiple HCCs (1).},
	issn = {2304-389X},	url = {https://hbsn.amegroups.org/article/view/26020}
}