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Histologic and molecular features of small well-differentiated pancreatic neuroendocrine tumors associated with the development of liver metastases

  
@article{HBSN25371,
	author = {Paula Jiménez-Fonseca and Patricia Morales del Burgo and Felipe Alvarez-Manceñido},
	title = {Histologic and molecular features of small well-differentiated pancreatic neuroendocrine tumors associated with the development of liver metastases},
	journal = {Hepatobiliary Surgery and Nutrition},
	volume = {8},
	number = {4},
	year = {2019},
	keywords = {},
	abstract = {The incidence of neuroendocrine neoplasms (NEN) has grown by a factor of 6.4 between 1973 and 2012 (1). According to the United States Surveillance, Epidemiology, and End Results (SEER), some 50% of all NEN, 3.56×105, are gastroenteropancreatic (GEP) in origin, including 1.05, 10.4, 0.48×105 of the small intestine, rectum, and pancreas, respectively. Like the Spanish group, others have reported a higher incidence of pancreatic NEN (P-NEN) (2). Given its typically indolent course, GEP-NENs are the second most prevalent tumors of the digestive system, surpassed only by colorectal cancer, underscoring the importance of understanding them, their diagnosis, and efficient treatment strategies.},
	issn = {2304-389X},	url = {http://hbsn.amegroups.com/article/view/25371}
}