Intraductal tubulopapillary neoplasm (ITPN) of pancreas with polycystic kidney and liver disease
Images in Clinical Medicine

Intraductal tubulopapillary neoplasm (ITPN) of pancreas with polycystic kidney and liver disease

Kwang Yeol Paik

Department of Surgery, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea

Correspondence to: Kwang Yeol Paik, MD, PhD. Department of Surgery, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 10, 63-ro, Yeongdeungpo-Gu, Seoul 07345, Republic of Korea. Email: kpaik@outlook.com.

Submitted Nov 24, 2019. Accepted for publication Jan 08, 2020.

doi: 10.21037/hbsn.2020.02.05


A 64-year-old man presented to pain in the left upper quadrant and weight loss. Findings on magnetic resonance imaging (MRI) of the abdomen included the filling of mass in whole pancreatic ducts with marked dilatation (Figure 1A,B, within yellow dots). Total pancreatectomy was performed and whole pancreas replaced by intraductal mass like lesion (Figure 1C). Mural nodules filled with the whole pancreas. Pathologic result revealed intraductal tubulopapillary neoplasm (ITPN) with invasive carcinoma. At a follow-up 4 years after surgery, he died with polycystic kidney infection without evidence of ITPN recurrence.

Figure 1 MRI finding indicate the mass in whole pancreas (A,B). Gross picture of ITPN filled with mass lesion in whole pancreas (C). MRI, magnetic resonance imaging; ITPN, intraductal tubulopapillary neoplasm.

ITPN is a rare pancreatic tumor belonging to a newly recognized entity that is updated in the 2010 WHO classification. It is definite difference between intraductal papillary mucinous neoplasm (IPMN). There were few reports of IPMN with polycystic kidney and liver disease but it is first report ITPN with polycystic kidney and liver disease on the literature.


Acknowledgments

Funding: None.


Footnote

Provenance and Peer Review: This article was not commissioned by the editorial office. The article was not sent for external peer review.

Conflicts of Interest: The author has completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/hbsn.2020.02.05). The author has no conflicts of interest to declare.

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Cite this article as: Paik KY. Intraductal tubulopapillary neoplasm (ITPN) of pancreas with polycystic kidney and liver disease. Hepatobiliary Surg Nutr 2020;9(4):562-563. doi: 10.21037/hbsn.2020.02.05