Is there a safe threshold for alcohol consumption in nonalcoholic fatty liver disease?

Mimi Kim, Dae Won Jun


Dose modest alcohol consumption (MAC) help the health care? There is a mainstream that MAC may not aggravate or even reduce cardiovascular disease and all-cause mortality (1,2). Light (≤3 drink/week) or moderate (>3 to ≤14 drinks/week for men or >3 to ≤7 drinks/week for women) alcohol consumption were reducing risk of mortality for all causes and cardiovascular disease (2). In 2018, combined analysis of 599,912 current drinkers in 83 prospective studies of high income countries, showed alcohol consumption was positive and curvilinear association with all-cause mortality and roughly linearly associated with a cardiovascular disease other than myocardial infarction (1). They recommend the threshold for lowest risk of all-cause mortality was 100 g/week.