An international expert consensus of management of recurrent hepatocellular carcinoma: a viewpoint

Kuniya Tanaka, Yuki Takahashi, Tetsuji Wakabayashi


We read with great interest the article titled “Multidisciplinary management of recurrent and metastatic hepatocellular carcinoma after resection: an international expert consensus” (1) published in HepatoBiliary Surgery and Nutrition. Recurrence can follow all treatments, representing a major challenge in treating hepatocellular carcinoma (HCC), as well as the main cause of death following surgery. Presently, guidelines and recommendations for primary HCC are clearly laid out, but recurrent HCC (RHCC) guidelines remain to be established—even though 70% of patients have recurrence within 5 years (2). This highlights the need for practical, stratified guidelines for continued management of these patients.

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